Turns On DNA In The Cells To Produce A Host Of Free Radical Fighting Enzymes!

Tuesday, December 1, 2009


TrueScience Product

Years of exposure to the sun, chemical toxins, and the free radicals released in the digestion process combined with the natural deceleration of your skin's ability to fight free radicals leave your skin without a fighting chance. The end result—aging, oxidative stress and less than beautiful skin.

TrueScience anti-aging skin cream applies cutting edge science to battle aging externally and contains the ingredients of Protandim, found to prevent cell damage internally. TrueScience gives skin a beautiful, even and smooth tone, diminishes fine lines and wrinkles, and provides a vibrant and glowing appearance.

Kimberly Stone, M.D and leading Denver-based board certified dermatologist declared, “I believe that LifeVantage TrueScience is a key complementary product to Protandim. The ravages of aging have a variety of causes and battling them at both the cellular and external levels is very important to long term health.”

How It Works
This new, proprietary skin care formula was developed in association with Kimberly Stone, M.D., a leading Denver-based board certified dermatologist, and was formulated with more of the ingredients known to protect the skin from the bombardment of factors that contribute to aging and the symptoms of unhealthy skin.

The TrueScience proprietary skin care formula includes:

Hydration/Moisturizing: TrueScience features a Lamellar Phase Emulsion System that forms a liquid emulsion barrier for superior moisturizing without a thick, oily feel. Moreoever TrueScience also contains extracts of sandalwood, phellodendron bark and barley, all of which deliver exotic fatty acids to retain the body’s natural moisture and produce a high-end moisturizing effect. Finally, it also features sodium hyaluronate, which is a superior moisture-binding agent that can balance moisture levels at the surface of the skin.

Toning/Brightening: The turmeric extract in TrueScience is specially modified to remove the majority of yellow compounds without reducing the effectiveness of its potent curcuminoids. Curcuminoids have been shown to produce a gentle skin lightening that even dispigmentation. Additionally, the leucojum aestivum bulb extract slows the spread of melanocytes, which contribute to uneven skin coloring.

Wrinkles/Fine Lines: The palm peptides and leucojum aestivum bulb extract in TrueScience are all shown to visibly reduce signs of wrinkles and fine lines. They may also help promote a thicker epidermis and dermis for less skin transparency for improved tone and texture.

All-Inclusive: Unlike most other skin care lines, the TrueScience anti-aging cream eliminates the need for an extra eye cream due to its wide ranging benefits.

Lipid Rejuvenation: TrueScience delivers multiple ingredients, including sandalwood oil, phellodendron bark extract, barley extract and a proprietary blend of glycolipids, soy phtosterols and hyaluronic acid to mimic the naturally occurring lipid structure in the skin and retain the body’s own moisturizing lipids. More Info



Study Concludes that Protandim Preserved Heart Function and Demonstrated Strong Cardioprotective Effects in an Animal Model of Lung Disease

Osteopontin levels reduced by more than 50%; heart output preserved and cardiac fibrosis prevented in animals

San Diego, CA, November 3, 2009, LifeVantage Corporation (OTCBB: LFVN), announced that in a peer-reviewed manuscript published in the prestigious American Heart Association journal Circulation, Dr. Norbert Voelkel and researchers at Virginia Commonwealth University (VCU), demonstrated the ability of Protandim, the Company’s patented dietary supplement composed of five highly synergistic “indirect antioxidants”, to protect the heart in a laboratory model of
pulmonary hypertension in rats.

Pulmonary hypertension is a health condition characterized by high blood pressure in the circulation between the heart and lungs and can result in death due to right heart failure. In this study, pulmonary hypertension was induced in the animals through a drug and by creating an oxygen-poor environment (hypoxia). Animals pre-treated with Protandim experienced strong cardioprotective effects. Protandim was shown to protect the heart by increasing the expression of protective genes and by preventing the formation of scar tissue, or fibrosis, in the heart.

The study showed that Protandim also prevented capillary loss in the heart muscle of the animals, preserving right heart function despite the continuing stress of pressure overload. Protandim also prevented the death of heart cells and significantly lowered osteopontin (OPN-1) levels by more than 50%. Osteopontin is a factor that leads to scar tissue formation, a cause of heart failure. The researchers in this study described the ability of Protandim to effectively activate the transcription factor Nrf2, a signal to the cell’s DNA to increase expression of a network of antioxidant, anti-inflammatory, and anti-fibrotic genes.

“We are encouraged by the results of this study, which was independently funded and independently conducted by Dr. Voelkel and his colleagues at VCU,” stated David Brown, President & CEO of LifeVantage.

“These results illustrate the unique antioxidant, anti-inflammatory, and anti-fibrotic properties of Protandim. Scientists have long known of the involvement of oxidative stress in disease processes, and this study is a significant example of how oxidative stress affects susceptibility to right heart failure in animals. Although it would be premature to conclude that similar benefits would be seen in humans, these remarkable results open the door to the possibility of future research on pulmonary hypertension and Protandim in humans.”

The study entitled “Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure” was authored by Harm Bogaard, Ramesh Natarajan, Scott C Henderson, Carlin Long, Donatas Kraskauskas, Lisa Smithson, Ramzi Ockaili, Joe M. McCord, and Norbert Voelkel was published online, with a print version to follow. More Info:

Saturday, November 7, 2009

Great News for Alzheimer's Patients and Care Givers, Diabetics, Cardiovascular Sufferers, and Everyone On Planet Earth

Great news for Alzheimer's patients and care givers, diabetics, cardiovascular sufferers, and just about everyone on the planet suffering from Oxidative Stress - the underlying cause of most of our ills!

Imagine having a clinically tested supplement that is natural and has no known negative side effects and works 100% of the time to help erradicate our ills caused by pollution! It may not be the answer to Al Gore's problem of environmental pollution but it may be the answer for the pollution of our cell environment in our bodies!

Jump for joy folks! We have hope and a secret weapon to combat environmental pollution, or its effects on our cells, from the inside out!

Look at what I found in this study, "Synergistic Induction of Heme Oxygenase-1 by the Components of the Antioxidant Supplement Protandim."

"Oxidative stress plays a significant role in the progression of many diseases, including diabetes, Alzheimer disease (AD), and atherosclerosis [1–3]. Oxidative stress generally results from an
imbalance between free radicals generated during normal cellular metabolism and the free radical or oxidant scavenging capacity of the endogenous antioxidant enzymes......"

"Protandim is a dietary supplement designed to induce endogenous antioxidant enzymes. It consists of five herbal ingredients, namely, silymarin from milk thistle (Silibum marianum), bacopa (Bacopa monniera) extract, ashwagandha (Withania somnifera), green tea (Camilia sinesis) extract, and curcumin from turmeric (Curcuma longa). The therapeutic properties of each of these herbs have been previously reported [9–11]. However, to gain optimal beneficial effects, the individual components may have to be used at pharmacological doses not easily achieved by oral administration and that could cause toxic side effects. Therefore, Protandim was formulated with the concept of combining multiple phytochemicals at low doses to gain synergy among them. A recent study demonstrated that administration (675 mg/day for 120 days) of Protandim in human subjects resulted in 30–50% increases in the activities of the antioxidant enzymes SOD and catalase in erythrocytes [12]. Furthermore, the age-dependent increase in circulating TBARS seen before treatment was completely suppressed after intake of Protandim. No undesirable side effects were observed, suggesting that Protandim is a safe nutraceutical supplement." - Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim, click here to see more of original

Charles Pace ND

Wednesday, November 4, 2009


Protandim is the only supplement clinically proven to reduce oxidative stress by an average 40%, slowing down the cell aging process to the level of a 20 year-old.* While conventional or direct antioxidants can neutralize only one free radical molecule, Protandim triggers the creation of enzymes that can each eliminate over a million free radical molecules per second without being used up.

Free radicals are the molecules that outside the human body cause rust in metals or cause browning in sliced apples. Free radical damage in the body is known as oxidative stress and plays a significant role in aging and cell damage. As we get older, our oxidative stress levels increase significantly—our bodies can’t keep up with the free radicals produced through the metabolic process.

Protandim is the only supplement clinically proven to reduce oxidative stress by slowing down the rate of cell aging to the level of a 20 year old and eliminating up to one million free radical molecules a second without being used up in the process.*

We say that Protandim is a “true” product because it is founded in the true science of free radical biology. By true, we mean that the science is backed by clinical studies, patents and is driven by one of the preeminent scientists in free radical biology and one of the co-discoverers of that field of science, Dr. Joe McCord.

For more information and to order product:

Tuesday, September 01, 2009

LifeVantage Granted Third Patent for Protandim® and Method for Reducing Important Inflammation Bio-Marker C-Reactive Protein

Elevated Basal Levels of C-Reactive Protein Are Considered Risk Factors for Diabetes, Hypertension, and Cardiovascular Disease

LifeVantage Corporation (OTCBB: LFVN), has been granted a third patent for its flagship product Protandim® from the United States Patent and Trademark Office. Protandim® has been clinically proven in earlier studies to slow the progressive rate of aging by reducing oxidative stress and this new patent further documents Protandim's® effect on antioxidant enzymes in vivo, describing anti-inflammatory effects such as the lowering of C-reactive protein.

C-reactive protein is widely considered by doctors and researchers as an indicator of the amount of inflammation present in the body. Elevated basal levels of C-reactive protein are considered risk factors for diabetes, hypertension, and cardiovascular disease. The patent, "Methods for Enhancing Antioxidant Enzyme Activity and Reducing C-Reactive Protein Levels," was issued on August 25, 2009.

Dr. Joe McCord, one of the foremost authorities on the body's antioxidant defense system and the co-discoverer of the important antioxidant enzyme superoxide dismutase or SOD, said, "This patent further underscores the unique and powerful actions of Protandim® as a tool against not only oxidative stress, but also inflammation. Chronic, low-level inflammation is now known to be associated with many of the major diseases we face as we age, including atherosclerosis, diabetes, obesity, and neurodegenerative diseases."

David W. Brown,
LifeVantage President and CEO commented, "The issuance of a third patent for Protandim® builds upon our previous two patents and further separates LifeVantage and Protandim® from other dietary supplements. It is difficult to receive a patent for a dietary supplement. Protandim® is uniquely and solidly based upon sound and proven science and the issuance of this third patent marks a historic day for LifeVantage, and sets an unparalleled standard in the dietary supplement industry."

Abstract of U.S. Patent No. 7,579,026: "Methods for Enhancing Antioxidant Enzyme Activity and Reducing C-Reactive Protein Levels":

An antioxidant-promoting composition that
increases antioxidant defense potential in a subject is disclosed comprising Bacopa monniera extract; milk thistle extract, ashwagandha powder, green tea extract, Gotu kola powder, Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetyl cysteine.

The antioxidant-promoting composition of the invention safely induces cellular antioxidant potential to achieve an overall net decrease in oxidative stress without the undesirable side-effects associated with the individual components of the antioxidant-promoting composition. Also disclosed is a method for reducing the undesirable side-effects of free radicals in a subject by administering to a subject in need of such antioxidants an effective amount of antioxidant-promoting composition of the invention.

About LifeVantage Corporation

LifeVantage Corporation is a publicly traded (OTCBB: LFVN), science-based, nutraceutical company dedicated to helping people reach their health and wellness goals.. Founded in 2003 and based in San Diego, Calif., LifeVantage develops products, including Protandim®, that deliver significant health benefits to consumers. For more information, visit

About Protandim®

Protandim® is a clinically proven supplement that provides substantial benefits for healthy aging. This patented indirect antioxidant therapy works in a very different way than conventional foods such as red wine, oranges, blueberries or other popular antioxidant supplements. Unlike those types of products that have proven to be largely ineffective in reducing oxidative stress caused by free radicals, Protandim® is an indirect antioxidant therapy, which stimulates the body's production of its own powerful antioxidant enzymes. Protandim® works at the cellular level, triggering cells to naturally increase production of protective antioxidant enzymes such as superoxide dismutase (SOD), catalase, and glutathione synthase.

A peer-reviewed human clinical study showed that after Protandim® was taken for 30 consecutive days, important biochemical markers of aging were decreased by an average of 40%. The study also reported that these markers of aging were reduced in the subjects taking Protandim® to the level of a typical 20-year-old.

Protandim® is currently the subject of approximately 20 scientific studies at leading universities and research facilities. The nature and stages of the studies vary, as some of the testing is at a preliminary stage, while other studies using Protandim® are currently in progress.

For more information about Protandim®, visit

If you need more information contact me Dr. Charles Pace ND: